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Furthermore, use the lowest effective dose for the shortest duration. Individualize. Take on an empty stomach. May give Opana as needed on an every 4–6hrs schedule; the oxymorphone ext-rel tab is given on a continuous basis every 12hrs. ≥18yrs: Opioid-naive: Opana: 10–20mg every 4–6hrs as needed. Ext-rel tab: Swallow whole; 5mg every 12hrs, titrate by 5–10mg every 12hrs every 3–7 days; if breakthrough pain occurs: adjust the dose or use small-dose rescue medication (eg, immediate-release oxymorphone). Again, OPANA is indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

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Generally, converting from Opana to an ext-rel tab: Give half the total daily Opana dose as oxymorphone ext-rel every 12hrs. Conversion from other opioids: see full labeling. However,

Peruse the Medication Guide gave by your drug specialist before you start taking oxymorphone and each time you get a top off. In the event that you have any inquiries, ask your primary care physician or drug specialist.

Take this drug by mouth without nourishment (in any event 1 hour prior or 2 hours in the wake of eating) as coordinated by your primary care physician, generally every 4 to 6 hours. On the off chance that you have a sickness, get some information about approaches to diminish queasiness, (for example, resting for 1 to 2 hours with as meager head development as would be prudent).

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